The commercial is being aired on TV in selected regions and is available on the official website and Youtube channel. The speech emphasizes Lineage’s core values: battle, Blood Pledge, sacrifice, and honor. The video showcases Kit delivering an epic speech to his Blood Brethren before battle. To celebrate the game launch, a TV ad featuring Game of Thrones ’ star Kit Harington is also revealed. Cross-play on console is also under preparation. Lineage W will be officially released later this 2021, but right now, eager players can sign up for the. New features expand automated data management solution with added scanner support and technology upgrades to improve data lineage experience. NCSOFTs CCO Taek-Jin Kim said, 'Lineage W is a project that pursues the ultimate Lineage' Supports quarter view based on full 3D graphics, a single build for the global market, and cross-platform. The game supports a single build for worldwide players, quarter view based on full 3D graphics and real-time AI translation. The business model (BM) has been drastically reduced. Lineage W was developed for global players with the concept ‘Worldwide’. Lineage W introduces a single build for the global market, which means that you will not be locked into a single region or platform. (Picture: NCSoft) We've established that Lineage W inherently supports cross-platform play, and the same goes for cross-progression. Lineage W is a new title succeeding the legitimacy of PC MMORPG Lineage. Lineage W features seamless cross-progression support. NCSOFT will expand service regions afterward to North America, South America, Europe, and Russia as well, but detailed schedules are yet to be revealed. NCSOFT’s multi-platform MMORPG Lineage W is now available for PC, iOS and Android in 12 countries and regions including Korea, Taiwan, Japan, Southeast Asia, and the Middle East. MANTA is a world-class data lineage platform that automatically scans your data environment to build a powerful map of all data flows and deliver it through a native UI and other channels to both technical and non-technical users.
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He had amazing video game skill when he was a pup and referred to by Shaggy as the Video Champ of Coolsville. He can stretch out his tongue to a rather impossible length. But his tail often gives him away while in disguise. Both his head and tail are malleable and useful as a communication aid or creating a distraction. He has a fully prehensile tail he can use to swing from or press buttons. Like many dogs he has an incredible sense of smell, earning his nose the nickname "Super Sniffer". When he was a puppy, Scooby Snacks would make him blast off like a rocket, before gliding gently back down to earth. He's shown to be a master dancer, as he got a perfect score on the WWE's victory dance, and avoided Kane's attacks. He also has a great sense of balance, as he can ride on a unicycle while juggling and balancing a fishbowl on his head. His tail is prehensile, being used to get him out of certain situations, if need be. He can also morph his body to mimic any and all monsters he has encountered, along with some humans, too. Dealing with Scrappy, would get him on his hind legs a lot, when he wanted to keep himself and Scrappy away from a monster. He can stand on his hind legs, which he gradually does more often as the years have gone by. He can also talk to other animals (mostly dogs), which comes in handy whenever the gang needs help or more information. He has peculiar and extraordinary abilities, such as being able to talk in English, although not without pronouncing most words as if they begin with an "R", though most people are able to understand him perfectly (if they acknowledge that he can speak at all). When he solves cases with his nephew Scrappy-Doo, he's very protective of him, as he often runs after him to prevent him from going straight to the monster or ghost. He has a rather mischievous side as he frequently pulls scare pranks and would snatch food from Shaggy. He also doesn't like being upstaged when someone does better than him and would try to prove otherwise. He enjoys a lot of attention and would sometimes appear brave and heroic. His catch phrase, usually howled at the end of every mystery, is "Scooby-Dooby-Doo!" or "Rooby-Rooby-Roo", sometimes followed by a quirky chuckle. Scooby-Doo and Shaggy share several personality traits, mostly being constantly hungry, being scared easily and most of the time refuse to help others, but their friends ( Velma Dinkley, Daphne Blake and Fred Jones) encourage them to go after the costumed villains usually with " Scooby Snacks", a biscuit-like dog treat or cookie snack (usually shaped like a bone or as shown in later versions of the cartoons Scooby's dog tag), though occasionally appealing to Scooby-Doo inherent loyalty and courage to take a more heroic stance. He has a black nose and wears an off-yellow, diamond shaped-tagged blue-green collar with an "SD" (his initials) and has four toes on each foot and unlike other dogs, Scooby only has one pad on the sole of each of his feet. Scooby also has opposible thumbs and can use his front paws like hands. He is generally a quadruped, but displays bipedal 'human' characteristics occasionally. Scooby is brown from head to toe with several distinctive black spots on his upper body. However, everyone who has seen the show will tell you that Scooby was the star of them all.Physical appearance For a full list of what Scooby wears, see Scooby-Doo's outfits and disguises One of the only characters to be added to the show was Scooby’s young nephew Scrappy Doo. Many of the characters appeared more than once. Some of these famous co-stars included Batman and Robin, Josie and the Pussycats, the Addams Family, the Three Stooges, and the Harlem Globetrotters. In the later version of the show, The New Scooby-Doo Movies, several guest stars would appear in the episode to help the team out, only to go their separate way at the end of the show. The crew would travel around in their Mystery Machine and solve supernatural happenings, which would usually turn out to be a criminal hiding their tracks or scaring someone away. The original story line had five main characters: Scooby Doo, Fred Jones, Daphne Blake, Velma Dinkley, and Scooby’s best friend Norville “Shaggy” Rogers. Of course, Scooby Doo costumes aren’t just about Scooby Doo. It is no wonder why people would want to dress up in Scooby Doo costumes every year for Halloween. The show has continued to be successful, even becoming several movies and spin-offs of the original series. The show was created to give concerned parents a break from some more violent cartoons that had been coming out in the time period, thus the more comedic characters and plots. When the first episode aired on Septemit was an immediate hit. Scooby Doo has got to be one of the top dogs (a Great Dane to be precise) on everyone’s list. Scumming is also how the Borg, a computer program which plays Angband, manages to win the game. Unfortunately, these regenerating levels also encourage a practice known as 'scumming' 3, where the player spends a long time at a depth at which they can easily survive until they finally feel tough enough to descend deeper (if you were to attempt this in a game with static dungeon levels such as NetHack, you would probably starve to death waiting for new monsters to appear). This means that you need to make hard choices about what equipment to keep, what to sell in the shops in town, and what to discard. Also, there is a limit to how many items you can carry at the same time (you have a home in town, but that too has a finite capacity). One distinctive feature of Angband is that when you leave a dungeon level, it and everything on it is gone forever. This protection is usually obtained through equipment such as artefact weapons and armour. The deeper you go into the dungeon, the more dangerous the monsters become, and the more important it becomes to have protection against these special attacks. Drain away your life (ie, experience points).Confuse you, making it impossible to run or fight effectively.Frighten you so that you cannot fight in melee.You can continue your adventure after killing Morgoth, but there isn't much point, unless you want to search for the One Ring which is rumoured to be buried in the dungeon somewhere.Īpart from simply thrashing you in combat, here are some of the nasty things that monsters can do to you: Eventually you will have to fight and kill Morgoth, who resides in the deepest dungeon level, in order to win the game 2. The object of the game is to kill Morgoth (the Dark Enemy of Middle Earth), by travelling through the dungeon amassing experience, equipment and (less importantly) treasure. In Angband you are represented by an symbol 1 and travel around the dungeon fighting lots of monsters (alphabetic characters in various colours) by either running into them (which represents hitting them with a melee weapon), shooting them or zapping them with an array of spells, wands and other magic devices. For those who are not familiar with this type of game, they are turn-based dungeon exploration and monster-killing games which generally use ASCII graphics. Angband is a Tolkien-based roguelike computer game, named after Morgoth's fortress of iron in JRR Tolkien's The Silmarillion. ☛Abundant backup plans like schedulable backup tasks, multi-version backup, flexible backup rotation, etc. Hyper Backup supports comprehensive backup destinations, including a local shared folder, an external device, another Synology NAS, a rsync server, or a public cloud service like Google Drive, Amazon Drive, Dropbox, Microsoft Azure, S3-compatible storage, and Synology C2, a cloud backup service dedicated to Synology users. It provides an intuitive and complete backup/restore solution to help you retain/restore copies of important data and restore applications and system configurations to a previous point in time. Synology Hyper Backup is a solution to back up various kinds of data (system configurations, shared folders, and applications/packages) on your Synology NAS manually or by schedule. Then it starts syncing Synology NAS to Dropbox. And click Next.Ħ. Press Apply to confirm the Synology Dropbox backup settings. Choose Google Drive as the destination to sync, and click Next to grant authority to Synology Cloud Sync, and allows Cloud Sync to access your Google Drive files.ĥ. Then choose a folder in Synology NAS as the Local path, Choose a folder in Google Drive to save the files from Synology NAS, and set the Sync direction: Bidirectional, Download remote changes only, or Upload local changes only. After installing, click Open to start Cloud Sync to backup Synology NAS to Google Drive:Ĥ. Double click Package Center, and click the All Packages tab, then scroll down to find Cloud Sync, and Install.ģ. Read below to learn how to get Synology backed up to Google Drive:Ģ. Steps to Backup Synology NAS to Google Drive with Synology Cloud Sync Whenever a file is modified, it must be re-downloaded and synced even if only partial modification was made. ☛Syncing mounted and external shared folder on the Synology NAS is not supported (EDS14 is excluded). ☛Upload and download file size limitations are imposed by cloud service providers. ☛Files with file name limitation imposed by cloud providers cannot be synced. ☛Speed and file size limitations are imposed by cloud service providers. ☛Centralized management for administrators to see which user is synchronizing files to certain cloud storage services, ensuring resource usage adheres to company policy and local laws. ☛Flexible and customizable options such as sync directions, encryption and compression, selective sync, schedule arrangements, and traffic control. ☛Safely and securely sync Synology NAS data to on-premise storage, private or public cloud storage services. After installing the Cloud Sync app from Synology's package manager (its app store), you only need to enable cloud services for each account you need. And the installation of it is very simple. You can synchronize multiple cloud services or multiple accounts belonging to one cloud service. Synology Cloud Sync is really simple, crisp, powerful, and functional. It allows one way or bidirectional syncing. What is Synology Cloud Sync?Ĭloud Sync is a service offered as part of the Synology NAS line, which can seamlessly sync your private data stored on Synology NAS to several public cloud services, including Google Drive, OneDrive, Dropbox, Amazon Drive and more. Cloud Sync and choose the suitable one according to your situations and needs. Many users have little acquaintance with these two Synology backup solutions so that they don’t know how to make a choice between them.Īctually, each of them has its own advantages and limitations, you can read on to learn the information of Synology Hyper Backup vs. Both Cloud Sync and Hyper Backup are popular backup solutions among Synology users. To help you protect your data in Synology NAS, Synology provides its users with various kinds of Backup solutions. With one or more data backups in hand, you can avoid the nightmare of losing all data at once. Therefore, you are recommended to backup your Synology NAS in advance. With the Quick Connect service of Synology NAS, you can access the NAS using a webpage or APP anytime, anywhere.Īctually, although NAS is regarded as a safe place for data storage, Unexpected data loss from hard drive failures, natural disasters, and ransomware attacks pose potential threats to your paramount data. With it, you can easily store the photos that carry precious memories, the music you love to listen to, and the collection of movies and the data in Synology NAS is safe and orderly. Synology is a type of NAS or Network Attached Storage. ColPortal allows one to perform multiomics analyses for groups of patients selected by their clinical data.Ĭolorectal cancer (CRC) is the second most commonly diagnosed cancer in Europe and the third leading cause of death worldwide. For each patient, demographic information, location, histology, tumor staging, tissue prognostic factors, molecular biomarker status and clinical outcomes are integrated with omics data. The current cohort consists of Caucasian patients from Europe. ColPortal also includes detailed information of histological features and digital histological slides from the study cases, since histology is a morphological manifestation of a complex molecular change. We present ColPortal, a platform that integrates transcriptomic, microtranscriptomic, methylomic and microbiota data of patients with colorectal cancer. Joint analysis of clinical and omics data can help clarify such relations. More recent evidence points to a causal role of microbiota and altered microRNA expression in CRC carcinogenesis, but their relationship with pathological drivers or molecular phenotypes is not clearly established. Different pathological pathways and molecular drivers have been described and some of the associated markers are used to select effective anti-neoplastic therapy. The following R packages have been used: limma 24, tidyverse 25, FactoMineR 22, factoextra 23, corrplot 29, minfi 26, 19 27, IlluminaHumanMethylation450kmanifest 28, cluster 30 and ape 31.Ĭolorectal cancer (CRC) is the third leading cause of cancer mortality worldwide. The result is a graph with the relations between categories.Īll scripts are developed in R 59 and they are used as templates, which are instantiated using the values defined by the user. This performs a multiple correspondence analysis with the selected variables. The results are a DM gene table and the methylation values (beta values) of each sample. This script performs a differential methylation (DM) analysis using raw data from Illumina microarrays. The color distinguishes the different groups of samples. This script generates a plot resulting from a principal components analysis (PCA) using the methylation values of the selected genes in the filtered samples, and the selected genus(s) (or families, or species). It is also necessary to know the number of microbiome variables (# numgenus#) and the number of genes (# numGenes#). An extra variable called “class” contains the labels of the classes. # m i c r o b i o m a G e n e s − M e t h y l a t e d # is a table whose variables are the microbiome data and the methylation levels of the genes for the selected samples. This script generates a correlation plot between microbial abundance and methylation data from selected DM genes obtained from samples previously filtered. Likewise, a second table with the normalized gene expression values per sample is generated. As a result, a table of DE miRNA is generated. This script reads preprocessed and normalized miRNA expression data and makes a differential expression (DE) analysis between the samples defined in parameter # U R L #. A second table with the normalized gene expression values per sample is also generated. As a result, a table of DE genes is generated. This script reads preprocessed and normalized expression data and makes a differential expression (DE) analysis between the samples defined in the parameter # U R L #. These are the scripts 58 used in the different analyses: Differences in expression profiling between tumoral colorectal carcinomas subsets and normal tissue and polyps Gene Expression Omnibus. Methyome profiling in serrated carcinoma. The Creative Commons Public Domain Dedication waiver applies to the metadata files associated with this article. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Dette er en populr sti for Backpacking, camping og Fottur, men du kan fortsatt oppleve fred og ro p roligere tidspunkt p dagen. Denne stien er vanligvis betraktet som en utfordrende rute og tar i gjennomsnitt 5 t 18 min fullfre. Looking south from Park Creek Pass at a sea of North Cascade peaksīack on SR20, this is Diablo Lake, from the Diablo Lake Overlook. Oppdag denne 12,4-km lange frem og tilbake-stien i nrheten av Stehekin, Washington. Looking up-valley towards (I think) Booker and Buckner mountains Going up the Park Trail to Park Creek Pass, you have to cross Park Creek on this log The old Stehekin Road - you can't get here in a vehicle any more, so it is now just a hiking trailįoot bridge over the roiling Stehekin River on the Flat Creek trail leading to Flat Creek Camp The confluence of the the north fork into Bridge Creek Storm King Mtn and others at the had of the North Fork Bridge Creek valley This is Liberty Bell Mountain as seen from the Washington Pass lookout on state route 20 NP staff told me that they work 8 days of 10 hour shifts at a go. You need a permit and to reserve each nights camp and cannot reserve ahead of time at this park.Īnd how about this for luck: the trail crew had logged out Bridge Creek in the days before I got there. For those who know the area, my four camps were Grizzly Creek, two nights at Flat Creek, and North Fork. One day was partly cloudy and the rest of the time was all sun. At the pass, you’re greeted by trickling streams of snowmelt and views of the peaks of Golden Horn and Mount Henry to the east. But the reward for your efforts is an eastside gateway into the stunning North Cascades National Park. But after the first couple of days it cooled down. Don’t be fooled by the name the way to Easy Pass is anything but easy. This east-slope hike at low altitude with a south-facing trail has the potential to be really hot. On the south side of the pass, there was almost no snow.īugs were out but moderate (more flies than mosquitoes) and the first few days were very hot. But the 17 mile RT/3800 foot gain dayhike to Park Creek Pass got me to about 6100 feet. The backpack was all fairly low altitude as the highest I camped was 3100 feet. It was an out-and-back because the north side of Park Creek Pass was still very snowy and I really don't mind out-and-backs. I did a 5-day backpack in the southern part of North Cascades National Park last week. This will be a fair amount of distance and turn you invulnerable for the duration of the animation sequence. I’m so excited to present some of the background evolution of the game, that I’ll be talking about myself in the third person for a bit. A month after Edgerunners, Cyberpunk 2077 is still getting 1 million active. Hey This is MekaSkull, the developer of Cyber Shadow: the retro-rooted, ninja-jumping, robot-slashing action platformer that is coming to PS4 and PS5 on January 26. While running, you have the option to slash forward. Video game release dates for PS5, Xbox Series X, PC, Switch, and more. If you then attack that orb, it sends back the projectile in the form of a slash-like wave. Cyber Shadow PlayStation 5 Yacht Club Games Release Date: Also On: PC, PlayStation 4, Switch, Xbox One Metascore 77 Generally favorable reviews based on 9 Critic Reviews User Score 6.6 Mixed or average reviews based on 11 Ratings Summary: The world has been taken over by synthetic lifeforms. The instant you deflect it, a stationary orb is created at the same spot. Knowing the effort that goes into such a project, Hunziker tells potential indie devs that they should keep going once theyve started, but 'dont sacrifice your health' in the process. Parry can be used to deflect incoming projectiles. Unlocks a multitude of traversal options in result. You will be able to slide to walls, whenever you bump onto them. The lightning strike allows you to strike enemies below you and bounce off them for strategic air-time. Rising fire can deal devastating damage at close range. They can also occasionally open paths you otherwise wouldn't be able to go through. This ability throws fire projectiles that are particularly useful for taking down flying foes. Retro Action Platformer Cyber Shadow Confirms January PS5 And PS4 Release Date Joe Apsey / DecemCyber Shadow, the next title from Yacht Club Games, has been given a PS5 and PS4. This is a throwing projectile that can damages enemies and turn on/off switches from afar. Cyber Shadow Brings Pixelated Ninja Action to PS5, PS4 in January 2021 Cyberpunk shinobi Subscribe to Push Square on YouTube We've been quietly looking forward to Cyber Shadow, a. When these abilities are upgraded additional functions become unlocked. These new abilities tend to be acquired later in the game and can be upgraded. In Cyber Shadow there are various abilities (powerups) you can pick up as you progress through the game which you can then use in earlier levels to access areas in them that you couldn't before. This may or may not work for other protection apps. sh installer, open your default terminal emulator, and run the following commands (dont forget to adapt the first command depending on the game and its location. When I re-installed it on my default Steam drive (the E drive in my case), it immediately eliminated the 'application load error' issue. I had it installed in a 'SteamLibrary' folder on a different drive, and that apparently caused the issue. Alternatively you may use the player.ini file fix to start it in windowed mode. Creating a GOG system report If you have installed the game using our. In my case, the error related to having Syberia installed on a drive other than the default Steam drive. You may hear audio but see nothing, but it should start (it did for me ) ) - you can then use Ctr+Alt+Del/Esc/Alt+Tab to switch back and forth and menu should appear. System Requirements OS: Windows XP/Vista/7/10 Processor: 1.5GHz CPU Memory: 512MB Hard Disk Space: 1.5GB Video Card: DirectX compatible graphics card with. Also I enabled XP SP3 compatibility on main game file, as well as all other options including run as administrator and disable desktop themes (it seems that resolution limit can be left unchecked for game to start normally). It seems to me that after switching to fullscreen, protection software attempts do display block/allow popup underneath and hangs everything. (Syberia 2) I mean the DirectX tab in the dgVoodoo control panel. When you write DirectX menu, do you mean the NVIDIA control menu I did switch that to app driven, but no difference, lines are still there. In the feature, we are looking at a very special project for the game Mount & Blade II: Bannerlord. In the DirectX menu you need to switch the texture filtering from 'Force anisotropic' to 'App driven'. do you have any firewall / protection software running? I had a similarly looking problem (black screen, no pc response, compatibility settings/color limit did not help) and managed to solve it by disabling Comodo Personal Firewall/Defense+ (closed app altogether, just enabling "game mode" didn't make it). Were giving away 10 x GOG keys for The Witcher 3. I don't know if it will be of any help, but. Download all files only from the official Microsoft website. During prophase, the cell becomes spheroid while the cytoplasm becomes more refractile and viscous and pale.Prophase is the first stage of mitosis which is characterized by the appearance of thin-thread like condensing chromosomes.By the end of this phase, the cell enters the division or M-phase of the cell cycle.įigure: Prophase.Cell division involves the enormous expenditure of energy, thus cell stores ATP in the G 2.During this phase, the synthesis of RNA and proteins required for the cell continues.G 2 phase is termed the second gap phase or resting phase of the interphase.Thus, at the end of the S phase, each chromosome has two DNA molecules and a duplicate set of genes.įigure: Late G 2.The replication of cytoplasmic DNA can take place at any phase in the cell cycle. S-phase involves the replication of nuclear DNA and the synthesis of histone proteins.Important events like the transcription of three types of RNAs, synthesis of regulatory proteins, enzymes required for DNA synthesis, and tubulin proteins along with other mitotic apparatus take place during this phase.However, during G 1 phase, several cell organelles increase in size and cell rapidly synthesizes different types of RNA and proteins.It is also termed as the “resting phase” as no DNA synthesis takes place during this phase.It is the longest phase of the cell cycle and is followed by the M phase of the previous cell cycle.A series of metabolic changes occur during this phase, all of which are divided into three subgroups.In interphase, metabolism of the cell increases, and it is often termed the most active phase of the cell cycle.Interphase is a part of the cell cycle where the cell copies its DNA as preparation for the M phase (mitotic phase).Mitosis is divided into the following phases based on the completion of one set of activities and the onset of the other. Replication of chromosomes and synthesis of proteins required for spindle fiber formation are formed prior to the onset of mitosis.įigure: Stages of mitosis. Mitosis is a part of the cell cycle and is preceded by the S phase of interphase and usually followed or accompanied by cytokinesis. One can edit the videos from his/her collection. The software has full source code integrated. This is an award winning software from Arboretum Systems. One can easily use this to create slideshows. This little software is also a great one for video editing. It is compatible for most of the operating systems. It is like a library for people who want to share and borrow video content which has been created. The video editing software is high end software which has features like:Īdvanced Level Animation Tools to create perfect animated bodies.Īccumulates multiple scenes into one file. Someone with no experience with Video Editing tool can have a hard time mastering it though. The popularity this software has can only be rivaled by very few in the market. This software is more suited for 3D video making. This is the popular video editor for 3D videos and it is commonly used for Rigging, Modeling, Texturing videos, animating, the simulation of smoke and water etc. It grants the user the control of the Subtitles.įile conversion between different formats is an easy task with AvideMux.įrom 2002, Blender has been at the top of popularity charts for video editing. Video and audio encoding can also be done with this software. Cutting, editing and cropping of videos can easily be done with it. It is compatible to all the known operating systems for smooth using. You can do multipurpose video editing with this software. You can Create Movie Trailers using the software It is good software to have for free for its features. For updating without moving to a new OS version of Mac, you have to buy it. Although it is free, you will only avail the free version when a new Mac OS releases. It is free video editing software that comes with the Mac OS every time a new one is released. The software can download, convert and edit videos from different websites. One can post the videos in YouTube and Facebook after editing them. The software can be a great converter as well. Picture-In-Picture videos, Title editing, transition effects, transitional videos can be created with this software.Īudio can be edited separately and then can be merged with the video. The Software not only edits video and audio, it can even edit photos for videos. The most talked about features of this software are: Due to the features that it has, it can easily be placed at the top when considering video editing software genre. Users can choose the editing mode based on their experience and editing needs. One is Easy Editor Mode and the other is the Full Featured Mode. Wondershare video Editor has two modes of use. The editor is very simple to use and suits every operating system be it windows or mac. This is perhaps the most compact video editor that one can ask for in current time. Top 5 MTS Video Editing Software Recommended Let us go over the specifications and shed light on the comparisons. My list includes Apple iMovie, Avidemux, Blender, HyperEngine AV Video Editing Software and last but not the least, Wondershare Filmora. To make your choice easier from thousands of software I am listing the top five in the business. For that, they use a number of video editing software that they get their hands on. There are many among us who like to give their videos an extra spark by editing them. We often tend to record our precious moments in video and tend to share them with others. |
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